According to the study, "it is well established that myocardial infarction (MI) associated with coronary artery bypass grafting (CABG) predicts a poor outcome. Nevertheless, cardioprotective therapies to limit myocardial injury after CABG are lacking."
The researchers hypothesized that since preclinical research shows curcuminoids decrease proinflammatory cytokines during cardiopulmonary bypass surgery and decrease the occurrence of cardiac cell death, they may provide a much-needed therapy.
The primary end point was the incidence of in-hospital myocardial infarction, which was found to be decreased from 30.0% in the placebo group to 13.1% in the curcuminoid group -- a 56% relative risk reduction. Read the entire article.
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